Table 1 Baseline characteristics of patients in each group.

From: Real-world retention rates of biologics in patients with rheumatoid arthritis

 

ABT

TCZ

IFX

ETN

ADA

GLM

CZP

p-value

Cases (no.)

67

84

74

224

86

44

25

 

Age (years)

69.1 ± 11.8

60.8 ± 15.3

51.6 ± 12.8

59.9 ± 16.1

61.9 ± 14.1

67.2 ± 9.75

61.2 ± 13.9

 < 0.0001

Male rate (%)

23.9

20.2

32.4

16.5

18.6

18.2

20

0.1475

Body weight (kg)

54.8 ± 14.4

55.5 ± 11.5

58.4 ± 12.8

53.9 ± 11.5

54.4 ± 12.1

55.2 ± 13.5

55.6 ± 12.5

0.2771

BMI

22.7 ± 4.2

22.6 ± 3.9

22.5 ± 3.7

21.9 ± 3.7

22.1 ± 3.6

23.2 ± 4.8

22.5 ± 3.5

0.4376

Order of biologic use (no.)

2

2.3

1.1

1.2

1.7

2

2

 < 0.0001

Biologic naïve patients (%)

52.2

21.4

95.9

81.7

46.5

50.0

36.0

 < 0.0001

ACPA positivity (%)

89.6

97.6

90.5

88.2

87.1

88.6

92

0.3094

RF positivity (%)

82.1

86.9

82.2

78.5

75.6

81.8

76

0.5908

PSL usage (%)

61.2

61.9

71.8

63.8

60

65.9

48

0.3755

MTX usage (%)

70.1

67.9

98.6

72.9

82.6

93.2

80

 < 0.0001

PSL dose (mg/day)

4.4 ± 2.7

5.2 ± 2.6

5.9 ± 2.8

5.4 ± 3.0

4.4 ± 2.2

4.5 ± 2.2

4.6 ± 2.0

0.0116

MTX dose (mg/week)

7.6 ± 3.7

8.5 ± 3.9

7.7 ± 2.6

6.9 ± 2.7

8.3 ± 3.9

7.6 ± 3.9

10.2 ± 3.8

 < 0.0001

  1. Data are shown as mean ± standard deviation, unless otherwise specified.
  2. BMI body mass index, ACPA anti-cyclic citrullinated peptide antibody, RF rheumatoid factor, PSL prednisolone, MTX methotrexate, ABT abatacept, TCZ tocilizumab, IFX infliximab, ETN etanercept; ADA adalimumab, GLM golimumab, CZP certolizumab pegol.