Table 6 Baseline characteristics of patients with biologic naïve or not.

From: Real-world retention rates of biologics in patients with rheumatoid arthritis

TNF inhibitor

Naïve

Second or later

p-value

Cases (no.)

325

128

 

Age (years)

58.8 ± 15.3

62.0 ± 14.5

0.0423

Male rate (%)

20.9

17.2

0.4331

Body weight (kg)

54.9 ± 11.4

55.3 ± 13.8

0.7427

BMI

22.1 ± 3.5

22.5 ± 4.4

0.3647

ACPA positivity (%)

87.2

92.2

0.1866

RF positivity (%)

78.6

85.2

0.1467

MMP3 (ng/ml)

267.8 ± 251.0

241.1 ± 268.3

0.3237

PSL usage (%)

62.3

64.8

0.6649

MTX usage (%)

82

79.7

0.5928

PSL dose (mg/day)

5.4 ± 2.8

4.8 ± 2.4

0.0274

MTX dose (mg/week)

7.6 ± 2.9

7.6 ± 3.9

0.5924

  1. Data are shown as mean ± standard deviation, unless otherwise specified.
  2. BMI body mass index, ACPA anti-cyclic citrullinated peptide antibody, RF rheumatoid factor, MMP3 matrix metalloprotainase-3, PSL prednisolone, MTX methotrexate, TNF tumor necrosis factor.