Figure 3

Bacteria of the Bacillus genus were enriched after 9 weeks of natto consumption. (A–C) The cladogram shows the microbial species with significant differences in the groups. Nodes indicate different groups, with the species classification at the level of phylum, class, order, family, and genus shown from the inside to the outside. The red (HCD) and green (HVK in A, NN in B, LVK in C) nodes in the phylogenetic tree represent microbial species enriched in a group, respectively. Yellow nodes represent species without significant differences. Diagrams were made by the LefSe galaxy server. (D) The percentage of bacillus genus in each group after 5 weeks (left panel) and 9 weeks (right panel) of induction. Data are shown as mean +/− SEM. HCD High-cholesterol diet. HVK High-vitamin K natto. LVK Low-vitamin K natto. NN Normal natto. n = 6 for HCD, HCD + HVK, HCD + LVK. n = 3 for HCD + NN.