Table 3 Analysis of PD-L1/PD1 in Oral leukoplakia.

From: Correlation of PD-1 and PD-L1 expression in oral leukoplakia and oral squamous cell carcinoma: an immunohistochemical study

 

Mild

Moderate/severe

Total

p value

Frequency

11

14

25

 

PD-L1 positive dysplastic basal epithelial cells (labelling index)

1 (9.1%)

4 (28.6%)

5 (20.0%)

0.227

PD-L1 negative

Tumour epithelial cells (labelling index)

10 (90.9%)

10 (71.4%)

20 (80.0%)

PD-L1 positive TAF (SID score)

4 (36.4%)

14 (100%)

18 (72.0%)

0.001

PD-L1 negative TAF (SID score)

7 (63.6%)

0 (0%)

7 (28.0%)

SID score of PD L1 positive TAFs (mean ± SD)

0.82 ± 1.168

2.86 ± 1.167

 

0.000

PD-1 positive TILs (labelling index)

8 (72.7%)

14 (100%)

22 (88%)

0.037

PD-1 negative TILs (labelling index)

3 (27.3%)

0 (0%)

3 (12.0%)

H-score of PD-1 positive TILs (mean ± SD)

54.73 ± 73.987

84.57 ± 61.405

 

0.282

  1. Significant values are in bold.