Table 1 SPR affinities for the interaction of SALL4 zinc fingers 1, 2, or 1–2 with immobilized DDB1:CRBN complexed with pomalidomide (POM) or CC-220 at 5 μM.

From: Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon

  1. “No binding” indicates no response for ZF1(370–409) and ZF2(405–432) at 25 μM. All results are duplicates (N = 2) unless noted.