Table 3 Changes of echocardiographic parameters from baseline to Week 24.
Baseline Mean (SD) | 24-Week mean (SD) | p value | |
|---|---|---|---|
LV mass (g) | 182.1 ± 51.8 | 187.1 ± 51.0 | 0.520 |
LV EDV (mL) | 105.7 ± 30.7 | 108.2 ± 33.1 | 0.649 |
LV ESV (mL) | 41.0 ± 17.8 | 41.0 ± 17.2 | 0.982 |
Left ventricular Ejection Fraction (%) | 61.8 ± 8.3 | 62.8 ± 7.5 | 0.308 |
Cardiac output (mL) | 4.9 ± 1.6 | 4.9 ± 1.9 | 0.971 |
Stroke volume index | 36.6 ± 10.2 | 38.4 ± 10.7 | 0.345 |
LV IVRT (ms) | 94.2 ± 11.3 | 96.5 ± 23.0 | 0.525 |
DT (ms) | 220.9 ± 48.3 | 226.1 ± 46.1 | 0.492 |
E (m/s) | 0.8 ± 0.2 | 0.7 ± 0.2 | 0.262 |
A (m/s) | 0.9 ± 0.2 | 0.9 ± 0.2 | 0.622 |
E/e' ratio | 11.3 ± 3.2 | 9.1 ± 2.9 | < 0.001 |
LV GLS (%) | 16.6 ± 2.8 | 18.0 ± 3.4 | < 0.001 |
LA Volume (mL) | 51.8 ± 16.5 | 46.6 ± 15.3 | < 0.001 |
PALS (%) | 23.6 ± 5.8 | 28.2 ± 7.4 | < 0.001 |
LA SRs | 1.3 ± 0.4 | 1.4 ± 0.5 | 0.006 |
LA SRe | 0.9 ± 0.3 | 1.3 ± 0.4 | 0.000 |
LA SRa | 1.3 ± 0.5 | 1.3 ± 0.6 | 0.611 |
LA stiffness | 0.5 ± 0.2 | 0.4 ± 0.2 | < 0.001 |
