Table 3 Correlations between clinical parameters and functional metabolic pathways (clinical parameters with |R|> 0.2 in fecal and gastric samples).
Consensus pathway of "NCD/HFD vs sHFD" and " Samczuk et al." | Description | Site | Compared group | Increased Group | Correlated clinical parameter with pathway (r) |
|---|---|---|---|---|---|
ko00063 | Glyoxylate and dicarboxylate metabolism | Fecal | NCD vs sHFD | sHFD | Glu_AUC (− 0.58) |
ko00430 | Taurine and hypotaurine metabolism | Fecal | HFD vs sHFD | sHFD | Diet_mean (− 0.46) |
ko00650 | Butanoate metabolism | Fecal | HFD vs sHFD | sHFD | Glu_AUC (− 0.35) |
Diet_mean (− 0.56) | |||||
ko00910 | Nitrogen metabolism | Fecal | NCD vs sHFD | sHFD | Glu_AUC (0.701) |
Leptin (0.689) | |||||
TG (0. 375) | |||||
LDL (0.701) | |||||
BW_mean (0.558) | |||||
ko00240 | Pyrimidine metabolism | Fecal | HFD vs sHFD | sHFD | Glu_AUC (− 0.739) |
Insulin (0.434) | |||||
Leptin (− 0.666)) | |||||
LDL (− 0.578) | |||||
BW_mean (− 0.472) | |||||
ko00970 | Aminoacyl-tRNA biosynthesis | Fecal | HFD vs sHFD | sHFD | Glu_AUC (− 0.766) |
Leptin (− 0.741) | |||||
LDL (− 0.671) | |||||
BW_mean (− 0.566) |
