Table 1 Characteristics of study participants based on SUA quartile, weighted.
Characteristic | Serum uric acid (mg/dL) | |||||
|---|---|---|---|---|---|---|
Total | Q1 (0.5–4.4) | Q2 (4.4–5.3) | Q3 (5.3–6.2) | Q4 (6.2–11) | P-value | |
N | 5895 | 1417 | 1490 | 1411 | 1577 | |
Age (years) | 42.803 ± 14.472 | 41.84 ± 14.65 | 42.88 ± 14.48 | 43.28 ± 14.47 | 43.19 ± 14.27 | 0.0281 |
Weight (kg) | 79.903 ± 18.136 | 68.62 ± 14.86 | 75.93 ± 15.93 | 83.98 ± 17.00 | 90.08 ± 16.80 | < 0.0001 |
Height (cm) | 169.562 ± 9.906 | 164.29 ± 7.90 | 167.58 ± 9.48 | 171.71 ± 10.21 | 174.22 ± 8.83 | < 0.0001 |
BMI (kg/m2) | 27.717 ± 5.613 | 25.39 ± 5.14 | 27.05 ± 5.38 | 28.51 ± 5.54 | 29.71 ± 5.42 | < 0.0001 |
Waist circumference (cm) | 95.442 ± 14.425 | 87.35 ± 12.73 | 92.65 ± 13.30 | 98.27 ± 13.48 | 102.78 ± 13.19 | < 0.0001 |
Calcium supplementation (mg) | 930.341 ± 552.087 | 901.94 ± 535.53 | 922.57 ± 532.66 | 933.40 ± 567.25 | 960.28 ± 568.76 | 0.0314 |
Serum creatinine (mg/dL) | 0.868 ± 0.171 | 0.76 ± 0.13 | 0.83 ± 0.15 | 0.91 ± 0.16 | 0.97 ± 0.16 | < 0.0001 |
eGFR (mL/min/1.73 m2) | 97.444 ± 18.027 | 102.11 ± 17.49 | 97.90 ± 18.18 | 96.29 ± 17.98 | 93.85 ± 17.46 | < 0.0001 |
Serum albumin (g/L) | 42.941 ± 3.063 | 42.28 ± 3.00 | 42.71 ± 3.03 | 43.04 ± 3.03 | 43.67 ± 3.02 | < 0.0001 |
Alanine aminotransferase (U/L) | 26.387 ± 18.451 | 20.44 ± 17.55 | 24.39 ± 16.07 | 27.71 ± 16.50 | 32.38 ± 20.76 | < 0.0001 |
Aspartate aminotransferase (U/L) | 25.684 ± 14.006 | 22.81 ± 18.06 | 24.67 ± 11.18 | 26.52 ± 11.95 | 28.46 ± 13.17 | < 0.0001 |
Alkaline phosphatase (U/L) | 66.558 ± 21.283 | 61.47 ± 19.97 | 66.24 ± 20.76 | 68.82 ± 22.43 | 69.44 ± 21.01 | < 0.0001 |
Blood urea nitrogen (mg/dL) | 12.017 ± 3.810 | 11.04 ± 3.46 | 11.77 ± 3.75 | 12.21 ± 3.72 | 12.95 ± 4.01 | < 0.0001 |
Serum calcium (mg/dL) | 9.460 ± 0.351 | 9.40 ± 0.36 | 9.45 ± 0.35 | 9.47 ± 0.33 | 9.52 ± 0.35 | < 0.0001 |
Cholesterol (mg/dL) | 200.399 ± 39.926 | 194.49 ± 37.01 | 200.94 ± 41.91 | 201.16 ± 38.90 | 204.56 ± 40.87 | < 0.0001 |
Serum phosphorus (mg/dL) | 3.781 ± 0.561 | 3.84 ± 0.52 | 3.80 ± 0.57 | 3.75 ± 0.56 | 3.74 ± 0.59 | < 0.0001 |
Total protein (g/L) | 71.388 ± 4.315 | 70.57 ± 4.26 | 70.96 ± 4.14 | 71.63 ± 4.32 | 72.30 ± 4.32 | < 0.0001 |
C-reactive protein (mg/L) | 0.346 ± 0.736 | 0.29 ± 0.56 | 0.33 ± 0.55 | 0.38 ± 0.91 | 0.38 ± 0.84 | 0.0009 |
HDL-C (mmol/L) | 1.377 ± 0.410 | 1.55 ± 0.42 | 1.43 ± 0.41 | 1.32 ± 0.39 | 1.23 ± 0.35 | < 0.0001 |
Total femur BMD(g/cm2) | 0.988 ± 0.146 | 0.92 ± 0.14 | 0.97 ± 0.14 | 1.01 ± 0.14 | 1.04 ± 0.13 | < 0.0001 |
Total spine BMD (g/cm2) | 1.042 ± 0.130 | 1.02 ± 0.13 | 1.04 ± 0.14 | 1.05 ± 0.13 | 1.06 ± 0.12 | < 0.0001 |
Total TBS | 1.402 ± 0.135 | 1.44 ± 0.11 | 1.42 ± 0.12 | 1.39 ± 0.14 | 1.36 ± 0.15 | < 0.0001 |
Gender (%) | < 0.0001 | |||||
Men | 50.772 | 13.35 | 37.05 | 66.31 | 83.24 | |
Women | 49.228 | 86.65 | 62.95 | 33.69 | 16.76 | |
Income to poverty ratio (%) | 0.247 | |||||
Low | 39.83 | 40.226 | 42.349 | 39.05 | 37.793 | |
Middle | 26.751 | 27.17 | 25.034 | 26.931 | 27.838 | |
High | 33.418 | 32.604 | 32.617 | 34.018 | 34.369 | |
Race/ethnicity (%) | 0.7084 | |||||
Mexican American | 9.003 | 9.19 | 9.79 | 8.87 | 8.25 | |
Other race/ethnicity | 10.328 | 11.13 | 9.42 | 11.06 | 9.79 | |
Non-Hispanic white | 70.578 | 69.51 | 70.52 | 69.98 | 72.12 | |
Non-Hispanic black | 10.09 | 10.18 | 10.27 | 10.1 | 9.84 | |
Education (%) | 0.0322 | |||||
Less than high school | 16.949 | 15.32 | 17.7 | 18.41 | 16.45 | |
High school | 24.073 | 22.04 | 26.09 | 24.14 | 24.02 | |
More than high school | 58.928 | 62.56 | 56.21 | 57.45 | 59.41 | |
Not recorded | 0.051 | 0.08 | 0.11 | |||
Marital status (%) | 0.0014 | |||||
Married/living with a partner | 66.487 | 66.71 | 63.49 | 66.25 | 69.21 | |
Widowed/divorced/separated | 15.326 | 16.41 | 17.55 | 15.67 | 12.03 | |
Never married | 18.138 | 16.81 | 18.82 | 18.08 | 18.77 | |
Not recorded | 0.049 | 0.06 | 0.14 | |||
Drinking status (%) | < 0.0001 | |||||
Yes | 75.186 | 66.11 | 72.25 | 78.41 | 83.19 | |
No | 21.378 | 29.42 | 24.8 | 17.95 | 14.05 | |
Not recorded | 3.436 | 4.48 | 2.95 | 3.64 | 2.76 | |
Smoke (%) | < 0.0001 | |||||
Yes | 25.536 | 22.54 | 25.93 | 28.76 | 25.04 | |
No | 22.031 | 17.31 | 18.63 | 23.23 | 27.43 | |
Not recorded | 52.433 | 60.15 | 55.45 | 47 | 47.53 | |
Sleep (%) | 0.0003 | |||||
< 6 h | 13.367 | 11.29 | 13.72 | 13.51 | 14.8 | |
= 6 h | 23.033 | 20.02 | 23.45 | 25.28 | 23.39 | |
7–8 h | 57.741 | 61.02 | 57.26 | 56.17 | 56.61 | |
> 8 h | 5.86 | 7.68 | 5.57 | 5.04 | 5.2 | |