Table 3 Threshold effect analysis of SUA on total TBS by using the two-piecewise linear regression model.

From: Cross-sectional analysis of the correlation between serum uric acid and trabecular bone score: NHANES 2005–2008

Total trabecular bone score

Adjusted β (95% CI), P-value

Serum uric acid

Fitting by the standard linear model

− 0.004 (− 0.006, − 0.002) 0.0003

Fitting by the two-piecewise linear model

 Inflection point

4.8

 Serum uric acid < 4.8 (mg/dL)

0.003 (− 0.002, 0.008) 0.1779

 Serum uric acid > 4.8 (mg/dL)

− 0.006 (− 0.009, − 0.004) < 0.0001

 Log likelihood ratio

0.002

  1. The model adjusts all variables except SUA and total TBS.
  2. Models adjusted for age, gender, race/ethnicity, education, marital status, income to poverty ratio, weight, height, BMI, waist circumference, calcium supplementation, drinking status, smoke, sleep, serum creatinine, eGFR, serum albumin, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, blood urea nitrogen, serum calcium, cholesterol, serum phosphorus, total protein, C-reactive protein, HDL-C, total femur BMD, total spine BMD.
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