Table 2 Activity of clotting factors and coagulation petameters, plasma protein and plasma properties in cryoprecipitates and ultrafiltered FFP units.
From: Hemostatic capability of ultrafiltrated fresh frozen plasma compared to cryoprecipitate
Coagulation factors | Cryoprecipitate | Ultrafiltration | p values |
|---|---|---|---|
VWF-RCo (IU/dL) | 615.2 ± 176.6 | 229.6 ± 71.8 | < 0.01 |
VWF:Ag (IU/unit) | 865.6 ± 284.3 | 275.7 ± 90.4 | < 0.01 |
Factor V (%) | 65.4 ± 11.6 | 256.3 ± 61.6 | < 0.01 |
Factor IX (%) | 129.3 ± 26.3 | 305.1 ± 54.8 | < 0.01 |
Factor VIII (%) | 486.9 ± 182.7 | 308.7 ± 79.1 | < 0.01 |
Factor XIII (%) | 176.2 ± 49.6 | 213.7 ± 53.7 | 0.028 |
Fibrinogen (mg/dL) | > 900 | 716.9 ± 143.8 | < 0.01 |
PT (s) | 13.7 ± 0.66 | 11.1 ± 0.5 | < 0.01 |
APTT (s) | 26.9 ± 2.3 | 27.9 ± 2.4 | 0.174 |
Antithrombin (%) | 89.5 ± 10.5 | > 150 | < 0.01 |
Total protein (g/dL) | 7.3 ± 0.6 | 15.9 ± 2.1 | < 0.01 |
Albumin (g/dL) | 3.6 ± 0.3 | 8.8 ± 1.0 | < 0.01 |
Osmotic pressure (mOsm/kg/H2O) | 304.0 ± 19.1 | 271.5 ± 9.3 | < 0.01 |
Volume (mL) | 52.1 ± 3.4 | 57.3 ± 11.6 | 0.07 |
Plasma density | 1.03 ± 0.002 | 1.047 ± 0.005 | < 0.01 |
EXTEM | |||
CT (s) | 54.7 ± 6.0 | 86.4 ± 14.6 | < 0.01 |
CFT (s) | 22.9 ± 3.5 | 69.1 ± 16.3 | < 0.01 |
Alpha angle | 85.7 ± 0.6 | 75.8 ± 4.3 | < 0.01 |
MCF (mm) | 65.0 ± 10.0 | 36.5 ± 8.2 | < 0.01 |
NATEM | |||
CT (s) | 718.5 ± 104.9 | 650.7 ± 119.1 | 0.067 |
CFT (s) | 193.4 ± 88.9 | 154.2 ± 63.5 | 0.123 |
Alpha angle | 64.2 ± 8.4 | 63.2 ± 8.4 | 0.729 |
MCF (mm) | 66.7 ± 10.4 | 34.4 ± 5.8 | < 0.001 |
