Table 3 Subset analysis of the levels of Factor VIII, VWF:Ag and VWF:RCo in FFP, ultrafiltration units, and cryoprecipitate from each blood type of donors.

From: Hemostatic capability of ultrafiltrated fresh frozen plasma compared to cryoprecipitate

 

A type

B type

O type

AB type

FFP

 VWF:RCo (IU/m)

76.8 ± 15.9

104.4 ± 20.4

76.6 ± 25.4

116.4 ± 20.8*

 VWF:Ag (IU/unit)

96.8 ± 24.3

131.4 ± 45.5

82.4 ± 18.5

144.6 ± 24.6*

 FVIII (%)

96.6 ± 21.9

123.9 ± 26.5

82.8 ± 22.0

131.6 ± 37.7*

 Fibrinogen (mg/dL)

217.6 ± 51.3

283.4 ± 99.8

309.0 ± 53.5

281.2 ± 43.8

 EXTEM-MCF

18.5 ± 3.4

21.2 ± 7.1

24.6 ± 3.6

19.6 ± 2.5

 NATEM-MCF

19.3 ± 2.2

23.0 ± 9.2

23.6 ± 3.8

22.0 ± 4.1

Ultrafiltration

 VWF:RCo (IU/m)

206.0 ± 72.8

234.6 ± 83.4

180.8 ± 24.0

296.8 ± 48.4*

 VWF:Ag (IU/unit)

222.4 ± 77.0

310.2 ± 112,0

221.6 ± 44.1

348.4 ± 55.7

 FVIII (%)

278.4 ± 57.3

314.2 ± 70.5

251.8 ± 62.5

390.5 ± 62.9*

 Fibrinogen (mg/dL)

634.0 ± 94.7

788.4 ± 131.5

799.0 ± 98.5

646.0 ± 177.8

 EXTEM-MCF

29.8 ± 2.9

38.6 ± 7.6

41.8 ± 9.2

34.4 ± 7.7

 NATEM-MCF

30.5 ± 3.1

36.0 ± 5.8

37.2 ± 5.4

33.0 ± 7.0

Cryoprecipitate

 VWF:RCo (IU/m)

619.4 ± 145.2

641.8 ± 81.1

458.4 ± 160.7

741.0 ± 208.1

 VWF:Ag (IU/unit)

874.8 ± 161.6

937.6 ± 289.8

609.0 ± 154.4

1040.8 ± 350.3

 FVIII (%)

492.4 ± 157.8

593.7 ± 259.4

356.8 ± 142.9

504.5 ± 100.0

 Fibrinogen (mg/dL)

> 900

> 900

> 900

> 900

 EXTEM-MCF

65.4 ± 4.7

65.6 ± 14.7

66.6 ± 7.7

62.4 ± 13.0

 NATEM-MCF

67.6 ± 7.3

65.8 ± 13.8

67.8 ± 9.7

65.6 ± 12.9

  1. Values are expressed as mean ± SD. Differences compared to the group O donors (*) are shown if results from two-way analysis of variance for repeated measures are significant (P < 0.05).
  2. FFP fresh frozen plasma, VWF:RCo von Willebrand factor ristocetin cofactor activity, VWF:Ag von Willebrand factor antigen, PT-INR prothrombin time-international normalized ratio, PT prothrombin time, APTT activated partial thromboplastin time, EXTEM extrinsic test, CT clotting time, CFT clot formation time, MCF maximum clot firmness, NATEM non-activated thromboelastometry, NA not assessed.