Figure 1 | Scientific Reports

Figure 1

From: Dihydrotanshinone I protects human chondrocytes and alleviates damage from spontaneous osteoarthritis in a guinea pig model

Figure 1

DHT alleviated the IL‐1β-induced decrease in cell viability of the human primary chondrocytes. (A) The 2D chemical structure of DHT. (B) The 3D chemical structure of DHT. (C) Cell viability of the human primary chondrocytes 24 h and 48 h after treatment with DHT in concentrations of 0, 0.5, 1, 2, 4, 8, and 10 μM. (D) Cell viability of the human primary chondrocytes after treatment with DHT of 2, 4, and 8 mM, followed by 3 h incubation with IL-1β (10 ng/ml). The data are presented as the mean ± SEM. #P < 0.05, ##P < 0.01, and ###P < 0.001 versus control; *P < 0.05, **P < 0.01, and ***P < 0.001 versus vehicle group.

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