Figure 3

DHT alleviated age-related deterioration of the subchondral bone in the tibial plateau of the guinea pig model. (A) Study design. (B) Representative sagittal images of the medial subchondral bone in the left tibial plateau. (C) Micro-CT parameters of the medial subchondral bone in the left tibial plateau of the guinea pig model. The data are presented as the mean ± SEM. #P < 0.05, ##P < 0.01, and ###P < 0.001 versus control; *P < 0.05, **P < 0.01, and ***P < 0.001 versus vehicle group.