Figure 4 | Scientific Reports

Figure 4

From: Dihydrotanshinone I protects human chondrocytes and alleviates damage from spontaneous osteoarthritis in a guinea pig model

Figure 4

DHT alleviated age-related deterioration of the articular cartilage in the tibial plateau of the guinea pig model. (A) Representative images of hematoxylin–eosin, Safranin O, and Alcian staining. Original magnification × 20. (B) The ratio of HC/CC and Mankin score for the 4-week treatment group. (C) The ratio of HC/CC and Mankin score of the 8-week treatment group. Data are presented as the mean ± SEM. #P < 0.05, ##P < 0.01, and ###P < 0.001 versus control; *P < 0.05, **P < 0.01, and ***P < 0.001 versus vehicle group.

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