Table 2 Diffusion tensor imaging analysis in disproportionately enlarged subarachnoid space hydrocephalus groups.

From: Relationship between disproportionately enlarged subarachnoid-space hydrocephalus and white matter tract integrity in normal pressure hydrocephalus

ROIs

FA

MD

AD

RD

Low DESH (n = 14)

High DESH (n = 19)

p

q*

Low DESH (n = 14)

High DESH (n = 19)

p

q*

Low DESH (n = 14)

High DESH (n = 19)

p

q*

Low DESH (n = 14)

High DESH (n = 19)

p

q*

Centrum semiovale

Lt

0.382 ± 0.058

0.357 ± 0.066

0.259

0.759

0.817 [0.749;0.947]

0.946 [0.800;1.070]

0.271

0.422

1.147 [1.050;1.402]

1.316 [1.066;1.441]

0.397

0.762

0.658 [0.603;0.784]

0.761 [0.648;0.871]

0.255

0.502

Rt

0.378 ± 0.083

0.336 ± 0.060

0.100

0.467

0.878 [0.783;0.967]

0.965 [0.846;1.138]

0.132

0.285

1.296 ± 0.213

1.345 ± 0.187

0.490

0.762

0.705 [0.570;0.794]

0.839 [0.682;0.947]

0.065

0.303

Corona radiata, anterior side

Lt

0.328 ± 0.071

0.308 ± 0.090

0.498

0.759

0.928 [0.854;1.092]

1.061 [0.920;1.279]

0.091

0.285

1.337 ± 0.158

1.470 ± 0.201

0.049

0.343

0.754 [0.678;0.947]

0.889 [0.743;1.120]

0.186

0.434

Rt

0.311 ± 0.081

0.290 ± 0.082

0.452

0.759

0.940 [0.849;1.005]

1.089 [0.941;1.218]

0.163

0.285

1.345 ± 0.238

1.421 ± 0.183

0.312

0.762

0.800 [0.690;0.841]

0.906 [0.753;1.066]

0.174

0.434

Corona radiata, lateral side

Lt

0.327 ± 0.064

0.279 ± 0.053

0.026

0.217

1.124 ± 0.208

1.268 ± 0.161

0.033

0.231

1.521 ± 0.224

1.652 ± 0.197

0.084

0.392

0.926 ± 0.206

1.075 ± 0.152

0.023

0.287

Rt

0.264 ± 0.058

0.269 ± 0.068

0.830

0.830

1.126 ± 0.231

1.333 ± 0.221

0.014

0.196

1.433 ± 0.249

1.719 ± 0.246

0.003

0.042

0.972 ± 0.227

1.140 ± 0.221

0.041

0.287

Post limb of internal capsule

Lt

0.7482 [0.702;0.771]

0.7474 [0.718;0.770]

0.529

0.749

0.808 ± 0.062

0.774 ± 0.068

0.148

0.285

1.630 ± 0.101

1.618 ± 0.119

0.777

0.777

0.360 [0.320;0.435]

0.334 [0.321;0.388]

0.287

0.502

Rt

0.757 [0.737;0.780]

0.748 [0.723;0.770]

0.653

0.762

0.782 [0.755;0.806]

0.766 [0.753;0.779]

0.114

0.285

1.623 [1.613;1.691]

1.617 [1.558;1.637]

0.226

0.762

0.335 [0.324;0.386]

0.338 [0.321;0.381]

0.815

0.878

Ant horn of lateral ventricle

Lt

0.343 ± 0.086

0.330 ± 0.043

0.651

0.762

0.942 [0.832;1.262]

0.968 [0.886;1.061]

0.928

0.928

1.327 [1.191;1.680]

1.330 [1.205;1.432]

0.760

0.777

0.780 [0.670;1.054]

0.809 [0.744;0.875]

0.900

0.900

Rt

0.360 ± 0.067

0.300 ± 0.081

0.031

0.217

0.957 [0.924;1.069]

1.005 [0.964;1.194]

0.132

0.285

1.362 [1.285;1.464]

1.389 [1.261;1.529]

0.733

0.777

0.780 [0.711;0.833]

0.874 [0.767;1.028]

0.091

0.318

Post horn of lateral ventricle

Lt

0.415 ± 0.090

0.424 ± 0.079

0.768

0.827

0.952 [0.826;1.124]

1.078 [0.893;1.186]

0.506

0.596

1.444 [1.287;1.558]

1.598 [1.330;1.751]

0.439

0.762

0.724 [0.599;0.872]

0.777 [0.719;0.916]

0.506

0.617

Rt

0.463 ± 0.071

0.446 ± 0.082

0.529

0.759

0.975 ± 0.184

1.023 ± 0.2007

0.495

0.596

1.487 ± 0.252)

1.524 ± 0.228

0.667

0.777

0.719 ± 0.167

0.773 ± 0.209

0.433

0.606

Corpus callosum

Genu

0.741 [0.626;0.779]

0.706 [0.43;0.755]

0.377

0.759

0.922 [0.849;1.131]

0.964 [0.881;1.064]

0.553

0.596

1.914 [1.842;0.252]

1.891 [1.815;2.009]

0.553

0.774

0.455 [0.364;0.714]

0.494 [0.399;0.628]

0.529

0.617

Splenium

0.724 ± 0.136

0.750 ± 0.107

0.542

0.759

0.847 [0.765;0.996]

0.810 [0.777;0.907]

0.553

0.596

1.847 ± 0.235

0.781 ± 0.178

0.362

0.762

0.363 [0.277;0.581]

0.375 [0.254;0.477]

0.397

0.606

  1. Data represent the mean ± standard deviation or median and interquartile ranges. Student t-test or Mann–Whitney U test were performed to compare DTI parameters in ROIs between two groups.
  2. Significant values are in [bold].
  3. DTI diffusion tensor imaging, DESH disproportionately enlarged subarachnoid space hydrocephalus, ROI region of interest, iNPH idiopathic normal pressure hydrocephalus, FA fractional anisotropy, MD mean diffusivity, AD axial diffusivity, RD radial diffusivity, Lt left, Rt right.
  4. *Adjusted for multiple comparison corrections using the False Discovery Rate (FDR) method.