Figure 5

Ultra-widefield fundus imaging of peripheral retinal changes associated with PROM1-related retinal degeneration. (A) The ultra-widefield fundus photograph of P3 presents only subtle peripheral retinal changes. (B) Ultra-widefield fundus autofluorescence illustrates a mild reticular pattern of hyperautofluorescence distributed in the periphery, which may be indicative of degenerative processes occurring in the peripheral retina. (C) Ultra-widefield fundus fluorescein angiography shows obvious peripheral retinal degeneration with vascular attenuation. Mild vascular leakage was also observed at the border of the peripheral retinal degeneration.