Table 1 Analysis of sex differences in Mir324 KO and WT mice.

From: Mir324 knockout regulates the structure of dendritic spines and impairs hippocampal long-term potentiation

   

# ♂

% ♂

# ♀

% ♀

Sex difference?

p

Fig

Mir324 KO

Spine density

Golgi

WT

4

50.00

4

50.00

No

p(interaction) = 0.86; p(sex) = 0.68

2A

KO

4

50.00

4

50.00

Thy1

WT

4

50.00

4

50.00

No

p(interaction) = 0.07; p(sex) = 0.17

2C

KO

4

44.44

5

55.56

Protein expression

Kv4.2

WT

9

52.94

8

47.06

No

p(interaction) = 0.20; p(sex) = 0.92

6A

KO

8

47.06

9

52.94

PSD95

WT

11

50.00

11

50.00

No

p(interaction) = 0.62; p(sex) = 0.57

2F

KO

12

66.67

6

33.33

MAP2

WT

11

50.00

11

50.00

No

p(interaction) = 0.36; p(sex) = 0.24

6E

KO

14

56.00

11

44.00

α-tubulin

WT

9

64.29

5

35.71

No

p(interaction) = 0.33; p(sex) = 0.92

6I

KO

13

50.00

13

50.00

β-actin

WT

10

50.00

10

50.00

No

p(interaction) = 0.27; p(sex) = 0.93

6 J

KO

11

45.83

13

54.17

β-tubullin

WT

7

53.85

6

46.15

No

p(interaction) = 0.47; p(sex) = 0.17

6G

KO

9

50.00

9

50.00

Synapsin

WT

7

50.00

7

50.00

No

p(interaction) = 0.36; p(sex) = 0.57

2H

KO

6

42.86

8

57.14

Characterization

Nesting

WT

16

42.11

22

57.89

No

p(interaction) = 0.89; p(sex) = 0.2)

1F

KO

21

55.26

17

44.74

Marble burying

WT

7

36.84

12

63.16

No

p(interaction) = 0.32; p(sex) = 0.22

1G

KO

12

4.44

15

55.56

Marble burying (latency)

WT

4

30.77

9

69.23

No

p(interaction) = 0.79; p(sex) = 0.52

Not shown

KO

11

47.83

12

52.17

miR-324-5p antagomir

Spine density

Scr

6

75.00

2

25.00

No

p(interaction) = 0.58; p(sex) = 0.52

3A

Antag

7

77.78

2

22.22

  1. No sex differences were detected in Mir324 KO and WT mice (2-Way ANOVA; p > 0.05 for all measures). For assessment of spine density and morphology in miR-324-5p or scrambled antagomir treated mice, note that including sex as a variable was underpowered.
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