Table 3 Risk factors associated with GVHD after LT (by Logistic regression analysis).

From: The effect of donor against recipient one-way HLA mismatch on liver transplantation outcomes from a multicenter registry analysis

Variables

Univariate

Multivariate

OR (95% CI)

p value

OR (95% CI)

p value

Sex (female)

0.51 (0.11–2.35)

0.385

  

Recipient age

1.03 (0.97–1.09)

0.323

  

Hypertension

0.95 (0.2–4.41)

0.948

  

Diabetes

1.59 (0.46–5.45)

0.461

  

D → R one-way MM

1 (Ref.)

 

1 (Ref.)

 

No one-way MM

3 loci

141.7 (30.99–647.97)

< 0.001

163.3 (34.15–780.89)

< 0.001

1 and 2 loci

62.98 (6.68–593.46)

< 0.001

91.85 (8.98–939.32)

< 0.001

Recipient BMI

1 (0.91–1.11)

0.939

  

CTP score

0.95 (0.75–1.19)

0.641

  

MELD score

0.97 (0.91–1.04)

0.393

  

LT type (LDLT vs. DDLT)

0.393

0.124

  

Re-LT

0 (0, inf)

0.989

  

GRWR

2.19 (0.77–6.20)

0.14

  

Cold ischemic time

1.07 (0.97–1.19)

0.072

1.09 (1.00–1.20)

0.052

Warm ischemic time

1.01 (1–1.01)

0.146

  
  1. MM mismatch, CTP child-turcotte-pugh, MELD model for end-stage liver disease, LDLT living donor liver transplantation, DDLT deceased donor liver transplantation, GRWR graft-to-recipient weight ratio.
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