Table 5 Clinical courses of cases of donor against recipient one-way HLA mismatch.
No. of D → R one way MM | Case no | Sex/Age | LT type (relationship) | HLA type | Reason for LT | MELD/PELD | GRWR (%) | Recurrence of liver disease | Surgical complication | Death (duration after LT) | Cause of death | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A | B | DR | DQ | |||||||||||
3 | 1 | |||||||||||||
Recipient | M/61 | LDLT | 24, 33 | 44, 62 | 7, 12 | HCC-B (TACE/RFA) | 11 | 0.75 | Bile duct stenosis & leakage/stone | Yes (10.7 months) | Graft failure d/t biliary complication | |||
Donor | F/25 | (Offspring) | 33, – | 44, – | 7, – | |||||||||
2 | ||||||||||||||
Recipient | M/41 | LDLT | 31, 33 | 44, 46 | 8, 13 | Alcoholic LC | 18 | 1.71 | Yes | Yes (1.9 months) | GVHD | |||
Donor | F/20 | (Offspring) | 33, – | 44, – | 13, – | |||||||||
3 | ||||||||||||||
Recipient | M/65 | LDLT | 2, 33 | 44, 62 | 4, 13 | HCC-C (TACE) | 9 | 1.17 | HCV | No | No | |||
Donor | M/40 | (Offspring) | 33, – | 44, – | 13, – | |||||||||
4 | ||||||||||||||
Recipient | M/54 | LDLT | 31, 33 | 44, 60 | 4, 7 | HCC-B | 13 | 1.02 | No | No | ||||
Donor | F/26 | (Offspring) | 33, – | 44, – | 7, – | |||||||||
5 | ||||||||||||||
Recipient | M/66 | LDLT | 24, 33 | 44, 46 | 7, 8 | HCC (beyond Milan) | 10 | 1.13 | Bile leakage | Yes (1.0 months) | GVHD | |||
Donor | F/38 | (Offspring) | 33, – | 44, – | 7, – | |||||||||
6 | ||||||||||||||
Recipient | M/53 | LDLT | 11, 33 | 44, 62 | 4, 7 | HCC-B (TACE) | 10 | 1.38 | HCC-B | No | Yes (10.6 months) | Infection | ||
Donor | M/28 | (Offspring) | 11, – | 62, – | 4, – | |||||||||
7 | ||||||||||||||
Recipient | M/66 | LDLT | 26, 33 | 44, 54 | 13, 14 | Alcoholic LC, HCC (beyond Milan) | 15 | 1.18 | No | Unknown (2.9 months) | ||||
Donor | M/39 | (Offspring) | 33, – | 44, – | 13, – | |||||||||
8 | ||||||||||||||
Recipient | F/57 | LDLT | 24, 33 | 51, 58 | 13, 14 | Alcoholic LC | 6 | 1.34 | No | No | ||||
Donor | F/33 | (Offspring) | 33, – | 58, – | 13, – | |||||||||
9 | ||||||||||||||
Recipient | M/64 | LDLT | 2, 31 | 51, 62 | 4, 15 | Alcoholic LC, HCC (TACE) | 11 | 1.79 | No | Yes (1.0 months) | GVHD | |||
Donor | M/34 | (Offspring) | 31, – | 62, – | 15, – | |||||||||
10 | ||||||||||||||
Recipient | F/10 | LDLT | 26, 33 | 37, 44 | 7, 10 | Biliary atresia | 1 | 1.32 | No | No | ||||
Donor | F/43 | (Parent) | 33, – | 44, – | 7, – | |||||||||
11 | ||||||||||||||
Recipient | F/33 | LDLT | 24, 33 | 44, 59 | 4, 13 | Alcoholic LC | 14 | 1.33 | No | No | ||||
Donor | F/32 | (Relatives) | 33, – | 44, – | 13, – | |||||||||
2 | 12 | |||||||||||||
Recipient | F/1 | LDLT | 2, 24 | 7, 51 | 1, 15 | Budd-Chiari syndrome | 11 | 2.78 | Hepatic vein stenosis/thrombosis (3 yr after LT) | No | No | |||
Donor | F/34 | (Parent) | 2, 24 | 7, – | 1, – | |||||||||
13 | ||||||||||||||
Recipient | F/67 | LDLT | 2, – | 50, 61 | 7, 15 | Drug toxicity | 29 | 0.94 | No | No | ||||
Donor | M/39 | (Offspring) | 2, – | 61, – | 15, – | |||||||||
1 | 14 | |||||||||||||
Recipient | M/48 | LDLT | 2, – | 60, 61 | 8, 14 | 5, 6 | HCC-B (Liver resection/ TACE/CCRT) | 15 | 1.01 | No | Yes (3.1 months) | GVHD | ||
Donor | M/17 | (Offspring) | 2, – | 61, – | 8, 14 | 5, 6 | ||||||||
15 | ||||||||||||||
Recipient | F/49 | LDLT | 3, 33 | 44, – | 13, – | Alcoholic LC | 9 | 1.68 | No | No | ||||
Donor | M/24 | (Offspring) | 33, – | 44, – | 13, – | |||||||||
16 | ||||||||||||||
Recipient | M/47 | LDLT | 2, 24 | 52, 62 | 14, 15 | HCC-B (TACE/beyond Milan) | 32 | – | HCC-B | No | Yes (47.0 months) | Recurred HCC | ||
Donor | F/17 | (Offspring) | 2, 24 | 62, – | 14, 15 | |||||||||
17 | ||||||||||||||
Recipient | F/51 | LDLT | 3, 33 | 44, 58 | 4, 13 | Unknown | 17 | 1.07 | No | No | ||||
Donor | M/20 | (Offspring) | 3, 33 | 44, 58 | 13, – | |||||||||
18 | ||||||||||||||
Recipient | M/57 | LDLT | 24, 26 | 7, 54 | 1, 4 | HCC-B (Liver resection/TACE) | 9 | 0.82 | Hepatic artery stenosis Post op bleeding | No | ||||
Donor | M/33 | (Offspring) | 24, – | 7, 54 | 1, 4 | |||||||||
