Table 3 PD-1/PD-L1 expression in immune cells of experimental and healthy control groups.

From: Altered levels of cytokine, T- and B-lymphocytes, and PD-1 expression rates in drug-naïve schizophrenia patients with acute phase

Variable

Experimental group

Healthy control group

t/χ2/Z

P

CD4+ T lymphocytes PD-1 expression (%)

14.68(9.25–22.89)

19.35(10.34–25.95)

− 0.19

0.46

CD4+ T lymphocytes PD-L1 expression (%)

41.15(5.96–68.14)

25.93(9.29–56.92)

− 0.54

0.60

CD8+ T lymphocytes PD-1 expression (%)

21.23 ± 8.87

17.29 ± 8.98

1.50

0.14

CD8+ T lymphocytes PD-L1 expression (%)

11.78(2.9–34.29)

13.13(4.62–30.82)

− 0.04

0.97

B lymphocytes PD-1 expression (%)

3.59 ± 2.27

1.85 ± 0.87

3.42

0.002**

B lymphocytes PD-L1 expression (%)

7.75(2.97–24.44)

7.43(4.36–12.29)

− 0.32

0.76

Mononuclear cells PD-1 expression (%)

0.06(0.04–0.14)

0.04(0.03–0.06)

− 1.88

0.06

Mononuclear cells PD-L1 expression (%)

0.04(0.01–0.29)

0.07(0.01–0.45)

− 0.17

0.87

NK cells PD-1 expression (%)

0.36(0.06–0.99)

0.13(0.09–0.21)

− 1.44

0.15

NK cells PD-L1 expression (%)

3.06(0.8–6.81)

3.65(1.04–12.59)

− 0.69

0.50

  1. **Significant at P < 0.01.
  2. Continuous variables conforming to normal distribution: mean ± standard deviation.
  3. Continuous variables that do not conform to normal distribution: median (25 percentile quantile, 75 percentile quantile).
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