Table 3 Expression level of eNOS, iNOS and COX-2 genes in the gastrictissue of the negative control group and groups orally administered Ca(OH)₂, CaTiO₃ or/and Y₂O₃ nanoparticles.

I

Negative control

1.00 ± 0.00^a

1.00 ± 0.00^a

1.00 ± 0.00^a

II

Ca(OH)₂ nanoparticles

0.91 ± 0.12^a

2.16 ± 0.06^b

2.06 ± 0.19^b

III

CaTiO₃ nanoparticles

1.54 ± 0.16^b

1.10 ± 0.01^a

1.12 ± 0.03^a

IV

Y₂O₃ nanoparticles

2.14 ± 0.07^c

1.00 ± 0.08^a

0.93 ± 0.05^a

V

Three nanoparticles

2.39 ± 0.14^d

1.02 ± 0.06^a

0.97 ± 0.04^a

One way analysis of variance (ANOVA)

F = 132.35

p < 0.001

F = 252.01

p < 0.001

F = 81.49

p < 0.001