Table 3 Improvement in hearing according to Siegel's criteria at 2 weeks and 2 months after treatment in the PS-matched cohort.

From: Treatment outcomes for idiopathic sudden sensorineural hearing loss in dialysis patients

1:5 propensity-score matched patients

 

Total (n = 282)

Dialysis group (n = 47)

Non-dialysis group (n = 235)

Crude model

Adjusted model

OR (95% CI)

P-value

OR (95% CI)

P-value

2-week follow up

 CR (%)

55 (19.5)

4 (8.5)

51 (21.7)

0.34 (0.10–0.88)

0.046

0.16 (0.03–0.64)

0.018

 PR (%)

36 (12.8)

5 (10.6)

31 (13.2)

0.78 (0.26–1.97)

0.633

0.88 (0.27–2.40)

0.810

 SR (%)

44 (15.6)

9 (19.1)

35 (14.9)

1.35 (0.57–2.94)

0.464

1.28 (0.49–3.07)

0.598

 No improvement (%)

147 (52.1)

29 (61.7)

118 (50.2)

1.60 (0.85–3.08)

0.152

2.08 (0.99–4.55)

0.059

 CR or PR (%)

91 (32.3)

9 (19.1)

82 (34.9)

0.44 (0.19–0.92)

0.039

0.34 (0.12–0.86)

0.03

 CR, PR or SR (%)

135 (47.9)

18 (38.3)

117 (49.8)

0.63 (0.32–1.18)

0.152

0.48 (0.22–1.01)

0.059

2-month follow up

 CR (%)

66 (23.4)

3 (6.4)

63 (26.8)

0.19 (0.04–0.53)

0.006

0.15 (0.03–0.57)

0.012

 PR (%)

44 (15.6)

8 (17.0)

36 (15.3)

1.13 (0.46–2.52)

0.769

1.07 (0.41–2.58)

0.881

 SR (%)

54 (19.1)

15 (31.9)

39 (16.6)

2.36 (1.14–4.71)

0.017

2.15 (0.94–4.80)

0.063

 No improvement (%)

118 (41.8)

21 (44.7)

97 (41.3)

1.15 (0.61–2.16)

0.666

1.41 (0.69–2.88)

0.344

 CR or PR (%)

110 (39.0)

11 (23.4)

99 (42.1)

0.42 (0.20–0.84)

0.019

0.36 (0.14–0.85)

0.025

 CR, PR, or SR (%)

164 (58.2)

26 (55.3)

138 (58.7)

0.87 (0.46–1.65)

0.666

0.71 (0.35–1.45)

0.344

  1. All ORs estimated based on patients not undergoing dialysis as a reference.
  2. Adjusted for baseline covariates including sex, age, body mass index, delayed time before treatment, diabetes mellitus, hypertension, treatment strategy, initial pure tone threshold at 500, 1000, 2000, 4000 Hz.
  3. CI confidence interval, CR complete response, OR odds ratio, PR partial response, PS propensity score, SR slight response.