Table 2 Comparisons of immunohistochemical assays and the corresponding average optical density between the pristine hydrogel and C-hydrogel groups.

From: Novel CO2-encapsulated Pluronic F127 hydrogel for the treatment of Achilles tendon injury

 

Pristine hydrogel group

C-hydrogel group

p

IOD

Area

AOD

SD

IOD

Area

AOD

SD

 

Muscle

 BMP-2

56,894.66

159,407.00

0.32

0.10

57,988.68

171,068.33

0.34

0.03

0.92

 TGF-β

32,977.62

96,746.00

0.34

0.04

38,094.70

124,233.00

0.31

0.02

0.5

 vWF

43,371.02

123,208.00

0.35

0.09

71,647.47

218,063.67

0.33

0.10

0.89

 VEGF

91,560.01

301,925.67

0.29

0.06

248,556.72

364,675.67

0.69

0.11

0.03*

Tendon

 Masson

462,395.42

1,155,094.67

0.40

0.03

604,866.06

1,301,671.33

0.46

0.03

0.11

 Col-I

164,190.54

288,166.33

0.39

0.02

369,426.60

498,765.00

0.74

0.02

0.0002*

 Col-III

144,808.28

292,189.00

0.45

0.08

58,319.24

182,322.33

0.32

0.02

0.19

  1. IOD, integrated optical density; AOD, average optical density; SD, standard deviation; BMP-2, bone morphogenic protein-2, TGF-β, tumor growth factor-beta; vWF, von Willebrand factor; VEGF, vascular endothelial growth factor; Col-I, collagen I; Col-III, collagen III.
  2. *Statistical significance.
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