Table 1 Basic demographic characteristics of the five groups by different Mg × K production for dialysis patients.
Variables | Group 1 (n = 89) | Group 2 (n = 89) | Group 3 (n = 89) | Group 4 (n = 89) | Group 5 (n = 88) |
|---|---|---|---|---|---|
Demographic factors | |||||
DM (%) | 51 | 42 | 47 | 46 | 44 |
Male (%) | 61 | 62 | 55 | 52 | 52 |
Age at study (years) | 64 ± 13 | 62 ± 13 | 64 ± 13 | 61 ± 12 | 62 ± 11 |
HD vintage, (months) | 4.7 ± 5.4 | 7.1 ± 6.1 | 7.3 ± 5.8 | 6.4 ± 5.7 | 7.1 ± 5.5 |
nPCR* (g/kg/day) | 1.29 ± 0.30 | 1.37 ± 0.28 | 1.37 ± 0.26 | 1.44 ± 0.31 | 1.45 ± 0.27 |
SBP (mmHg) | 134.5 ± 27.5 | 137.7 ± 33.4 | 134.8 ± 28.8 | 137.9 ± 27.7 | 137.1 ± 24.1 |
DBP (mmHg) | 73.6 ± 12.8 | 73.7 ± 15.4 | 72.9 ± 14.0 | 75.6 ± 16.9 | 75.0 ± 13.5 |
UF (L/session) | 2.4 ± 1.0 | 2.3 ± 1.0 | 2.4 ± 0.9 | 2.4 ± 1.0 | 2.3 ± 0.9 |
BMI (kg/m2) | 23.0 ± 3.5 | 23.8 ± 4.7 | 23.3 ± 3.9 | 23.1 ± 4.6 | 22.2 ± 3.6 |
Clinical comorbidity (%) | |||||
CAD (%) | 40 | 34 | 28 | 24 | 30 |
CHF (%) | 12 | 9 | 9 | 6 | 8 |
Peripheral vascular disease | 13 | 8 | 4 | 7 | 6 |
Liver cirrhosis and/or hepatoma | 3 | 3 | 6 | 6 | 1 |
Davies comorbidity score (%) | |||||
0 | 26 | 33 | 26 | 31 | 39 |
1–2 | 49 | 51 | 57 | 55 | 44 |
> = 3 | 25 | 17 | 17 | 13 | 17 |
Laboratory data | |||||
hs-CRP (mg/L) | 6.3 (2.1–12.6) | 4.0 (2.0–6.3) | 3.8 (1.4–10.5) | 4.3 (1.4–10.9) | 2.1 (1.0–5.3) |
Median (1st–3rd QR) | |||||
Pre-albumin (mg/dl) | 28.5 ± 8.7 | 26.7 ± 7.1 | 30.3 ± 8.1 | 31.8 ± 7.6 | 32.9 ± 6.3 |
Albumin (g/dl) | 3.64 ± 0.50 | 3.88 ± 0.30 | 3.86 ± 0.29 | 4.00 ± 0.33 | 4.00 ± 0.28 |
Product of Mg × K | 7.87(7.03–8.12) | 9.37(8.97–9.86) | 10.95*(10.50–11.26) | 12.3(11.87–12.82) | 14.92(14.07–16.23) |
iPTH, median, pg/mL | 243.6 | 234.7 | 371.5 | 273.7 | 327.0 |
(1st–3rd QR) | (114.3–652.2) | (95.6–458.9) | (138.0–655.1) | (113.0–604.0) | (177.5–758.4) |
Sodium (mmol/dL) | 138.6 ± 4.5 | 139.1 ± 2.7 | 139.4 ± 3.0 | 138.8 ± 2.7 | 139.0 ± 2.8 |
Potassium (mmol/dL) | 3.5 ± 0.5 | 4.0 ± 0.4 | 4.4 ± 0.4 | 4.7 ± 0.5 | 5.2 ± 0.6 |
Magnesium (mg/dl) | 2.1 ± 0.3 | 2.4 ± 0.2 | 2.5 ± 0.2 | 2.7 ± 0.3 | 3.0 ± 0.4 |
Corrected Calcium (mg/dl)# | 9.1 ± 0.8 | 9.3 ± 0.8 | 9.3 ± 0.7 | 9.4 ± 0.9 | 9.3 ± 0.8 |
Phosphate (mg/dl) | 4.3 ± 1.3 | 4.9 ± 1.3 | 5.0 ± 1.1 | 5.2 ± 1.5 | 5.4 ± 1.4 |
Cholesterol (mg/dl) | 163 ± 43 | 166 ± 40 | 160 ± 39 | 174 ± 46 | 174 ± 43 |
BUN (mg/dl) | 57.3 ± 17.3 | 60.3 ± 15.4 | 67.0 ± 15.6 | 68.5 ± 18.0 | 70.7 ± 18.4 |
Creatinine (mg/dl) | 9.0 ± 3.2 | 10.4 ± 2.4 | 10.5 ± 2.8 | 10.9 ± 2.8 | 11.0 ± 2.8 |
Uric acid (mg/dl) | 6.7 ± 1.9 | 6.9 ± 1.7 | 7.0 ± 1.5 | 7.1 ± 1.6 | 7.1 ± 1.4 |
Hemoglobin (g/L) | 9.8 ± 1.6 | 10.2 ± 1.4 | 10.1 ± 1.5 | 10.2 ± 1.2 | 10.4 ± 1.6 |
K: 3.5–4.0 (mmol/dL) (n) (%) | 7 (7.9) | 11 (12.4) | 4 (4.5) | 12 (13.5) | 10 (11.4) |
Mg: 2.1–2.4 (mg/dl) (n) (%) | 31 (34.8) | 36 (40.4) | 29 (32.6) | 31(34.8) | 24 (27.3) |
Medications, n (%) | |||||
Mg containing agents | 9 (10) | 4 (4) | 13 (15) | 11 (12) | 8 (9) |
Diuretics | 41 (46) | 42 (47) | 43 (48) | 35 (39) | 30 (34) |
Proton pumping agents | 12 (13) | 4 (4) | 12 (13) | 6 (7) | 8 (9) |
Vitamin D3 | 28 (32) | 30 (34) | 38 (43) | 37 (42) | 37 (42) |
