Figure 5

Outcomes of intracellular absorption of rhodamine B-labeled DOX-loaded (PAA-b-PCL-SS-PCL-b-PAA) NPs and rhodamine B-labeled (PAA-b-PCL-SS-PCL-b-PAA) NPs in various time intervals: 0.5, 1.5 and 3 h, at TME using flow cytometry (A); Graphs of mean fluorescence intensity (%) of intracellular uptake of RhB-labeled blank and DOX-loaded (PAA-b-PCL-SS-PCL-b-PAA) NPs in diverse time breaks: 0.5, 1.5 and 3 h, using flow cytometry; (diversities among treatments were statistically meaningful with the p-value ˂ 0.001) (B); Cytation 5 cell imaging multi-mode images of RhB-labeled blank and DOX-loaded (PAA-b-PCL-SS-PCL-b-PAA) NPs internalization at 0.5, 1.5 and 3 h. (All of them are treated by MDA-MB-231 cell lines) (C).