Figure 5

Effects of captopril on the expression of RAS markers in the liver from 129 and 129sve 5LO^−/− mice. (A,B) Agt gene expression in the liver of Wt, Cap, T1D, T1D + Cap, 5LO^−/−, 5LO^−/− + Cap, 5LO^−/− T1D and 5LO^−/− T1D + Cap mice groups. C and D: At1 gene expression in the liver of Wt, Cap, T1D, T1D + Cap, 5LO^−/−, 5LO^−/− + Cap, 5LO^−/− T1D and 5LO^−/− T1D + Cap mice groups. Agt and At1 gene expression was analyzed using liver homogenate from the groups mentioned. n = 5–8 mice per group. Data are displayed as mean ± SEM. Different superscripts lowercase letters means statistical significance, with p being at least < 0.05. One-way ANOVA followed by Bonferroni post-test was used to analyze this set of data.