Figure 1

Comparisons of alpha-diversity and beta-diversity between normal controls (NC), CAC mice and Inhibitor-treated CAC mice. N = 6 per group. (A) Number of observed OTUs and Shannon diversity index were significantly reduced in CAC group compared with NC and Inhibitor groups. *P < 0.05. (B) PCoA of unweighted UniFrac analysisshowed that thecolonic mucosa microbiota composition was different between NC, CAC and Inhibitor groups (P = 0.001). (C) Comparison of proportions of gut microbiotaon the bacterial genus levels between NC and CAC groups. *P < 0.05, **P < 0.01.