Table 4 Univariate and multivariate analysis for overall survival in the entire cohort.

From: The prognostic value of radiological and pathological lymph node status in patients with cervical cancer who underwent neoadjuvant chemotherapy and followed hysterectomy

Characteristics

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

Age (≤ 50 vs. > 50)

1.429

0.552–3.697

0.462

   

NACT cycle (≤ 2 vs. > 2)

1.083

0.318–3.686

0.898

   

Baseline tumor size (≤ 4 vs. > 4)

1.417

0.519–3.873

0.496

   

Tumor size after NACT (≤ 4 vs. > 4)

1.128

0.378–3.371

0.829

   

Response to NACT (No vs. Yes)

0.471

0.198–1.118

0.088

   

FIGO stage (IB-IIB vs. IIIC)

2.121

0.890–5.056

0.090

   

Tumor type (SCC vs. Non-SCC)

5.118

2.144–12.219

 < 0.001

5.691

2.344–13.815

 < 0.001

Differentiation (Well and moderately vs. Poorly)

2.098

0.881–4.995

0.094

   

LVSI (No vs. Yes)

5.150

2.062–12.863

 < 0.001

5.652

2.227–14.345

 < 0.001

Stromal invasion depth (≤ 2/3 vs. > 2/3)

3.076

1.293–7.317

0.011

   

Perineural invasion (No vs. Yes)

4.272

1.404–12.997

0.011

   

Corpus involvement (No vs. Yes)

1.643

0.692–3.901

0.261

   

Vaginal involvement (No vs. Yes)

1.940

0.569–6.610

0.290

   

Incision margin (No vs. Yes)

4.103

0.951–17.704

0.058

   

Parametrial involvement (No vs. Yes)

4.406

1.295–14.986

0.018

   

Adjuvant radiation (No vs. Yes)

1.984

0.800–4.921

0.139

   

Adjuvant chemotherapy (No vs. Yes)

20.951

0–3088071

0.616

   

LNr (No vs. Yes)

0.978

0.376–2.546

0.964

   

LNp (No vs. Yes)

3.559

1.496–8.469

0.004

   
  1. HR hazard ratio, CI confidence interval, NACT neoadjuvant chemotherapy, FIGO The International Federation of Gynecology and Obstetrics, SCC squamous cell carcinoma, LVSI lymph-vascular space invasion, LNr radiological lymph node status, LNp pathological lymph node status.
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