Table 3 Correlation analysis between PKM2 and marker genes of immune cells in GEPIA.

From: PKM2 is a potential prognostic biomarker and related to immune infiltration in lung cancer

Description

Gene markers

LUAD

LUSC

Normal

Tumor

Normal

Tumor

R

p

R

p

R

p

R

p

CD8+ T cell

CD8A

0.023

0.86

− 0.061

0.18

− 0.11

0.46

− 0.18

***

T cell (general)

CD3D

− 0.12

0.37

− 0.14

**

− 0.094

0.52

− 0.24

***

CD3E

− 0.045

0.74

− 0.16

***

− 0.052

0.72

− 0.21

***

CD2

− 0.11

0.41

− 0.13

**

− 0.073

0.61

− 0.22

***

B cell

CD19

0.021

0.88

− 0.27

***

0.054

0.71

− 0.16

***

CD79A

0.035

0.79

− 0.28

***

− 0.1

0.48

− 0.19

***

Neutrophils

CD66b

0.029

0.83

− 0.11

*

0.13

0.37

− 0.1

*

CCR7

0.081

0.54

− 0.18

***

0.0036

0.98

− 0.18

***

Dendritic cell

HLA-DPB1

0.17

0.2

− 0.12

**

0.35

*

− 0.13

**

HLA-DQB1

− 0.044

0.74

− 0.11

*

− 0.076

0.6

− 0.083

0.067

HLA-DRA

0.12

0.38

− 0.091

*

0.22

0.13

− 0.13

**

HLA-DPA1

0.15

0.26

− 0.071

0.12

0.056

0.27

− 0.13

**

CD1C

− 0.12

0.38

− 0.12

*

0.12

0.39

− 0.072

0.11

ITGAX

0.35

**

− 0.037

0.42

0.3

*

− 0.089

*

Th1

T-bet

− 0.099

0.46

0.094

*

0.069

0.63

− 0.21

***

STAT4

− 0.11

0.41

− 0.002

0.97

− 0.12

0.4

− 0.083

**

STAT1

0.0099

0.94

0.26

***

0.36

**

0.029

0.53

IFN-γ

− 0.17

0.2

0.057

0.21

− 0.26

0.07

− 0.12

**

Tfh

IL21

− 0.008

0.95

0.026

0.56

0.043

0.77

− 0.17

***

Th17

STAT3

0.14

0.29

0.11

*

0.3

*

0.16

***

Treg

FOXP3

0.15

0.25

− 0.021

0.64

0.077

0.6

− 0.12

**

STAT5B

− 0.054

0.69

− 0.055

0.23

0.2

0.17

− 0.092

*

TGFβ

0.46

***

0.17

***

0.53

***

0.33

***

T cell exhaustion

PD-1

0.082

0.54

0.011

0.82

0.069

0.63

− 0.22

***

CTLA4

0.032

0.81

− 0.017

0.72

− 0.092

0.53

− 0.19

***

LAG3

0.057

0.67

0.017

0.71

0.21

0.14

− 0.14

**

GZMB

− 0.17

0.21

0.084

0.063

0.66

0.063

− 0.17

***

  1. *p < 0.05, **p < 0.01, ***p < 0.001.