Figure 6 | Scientific Reports

Figure 6

From: Inhibition of Drp1 orchestrates the responsiveness of breast cancer cells to paclitaxel but insignificantly relieves paclitaxel-related ovarian damage in mice

Figure 6

Change in mice body weight, ovarian weight, follicular count, and E2 and AMH levels. Mice body weight (A) after various treatments were compared to the initial body weight (Day 0), ovarian weights of treated groups were compared to the corresponding control group (B). Differential follicular count demonstrated massive decrease of the count of various types (C). Both E2 (D) and AMH (E) decreased in PTX or cisplatin groups, whereas cotreatment with mdivi-1 did not show significant improvements compared to PTX or cisplatin groups. Data are shown as bars or dots indicating the mean (± SD). Abbreviations: E2: estradiol, AMH: antimullerian hormone.

Back to article page