Figure 1
From: Myeloid deletion of talin-1 reduces mucosal macrophages and protects mice from colonic inflammation
Myeloid cell-specific deletion of Tln1. BMmacs were generated form Tln1fl/fl and Tln1Δmye mice and infected with C. rodentium. (A) Expression of Tln1 mRNA determined by RT-real-time PCR 6 h post-infection; n = 3–4 mice per genotype. (B) Western blot of talin-1 protein (270 kDa) expression and (C) densitometry analysis at 24 h post-infection; n = 3 mice per group. All values are reported as mean ± SEM. Statistical analyses, where shown; *P < 0.05 determined by 1-way ANOVA and Tukey post hoc test.
