Figure 6 | Scientific Reports

Figure 6

From: Peri-implantitis increases the risk of medication-related osteonecrosis of the jaws associated with osseointegrated implants in rats treated with zoledronate

Figure 6

Dental implant and transmucosal healing screw characteristics and regions of interest (ROIs) evaluated in the present study. (a) Schematic drawing of the structure and dimensions of the dental implant and transmucosal healing screw. (b) Photograph showing the dental implant and the transmucosal healing screw separately and coupled to each other. Radiographic (c,d) and microtomographic (e) aspect of the dental implant after eight weeks of its installation in the maxilla (osseointegrated implant). (f) Schematic drawing showing the position of the dental implant in the maxilla of the rat and representation showing the ROIs analyzed in this study. In ROI1 the histopathological and PTBT analyzes were performed (black rectangle), in ROI2 the PNVBT analysis was performed (blue rectangles), in ROI3 the analyzes of OCN and TRAP were performed (red rectangle) and in ROI4 the analyzes of TNFα, IL-1β, VEGF (green rectangle) were performed.

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