Figure 2 | Scientific Reports

Figure 2

From: Overexpression of microRNA-205-5p promotes cholangiocarcinoma growth by reducing expression of homeodomain-interacting protein kinase 3

Figure 2

miR-205-5p knocking down affects KKU-213B CCA cell proliferation, migration, and invasion in vitro. (a) Relative expression of miR-205-5p to miR-16 as the internal control in the KKU-213B CCA cell line at 48 h after transfection with a miR-205-5p inhibitor, (b) Relative proliferation rates of KKU-213B cells transfected with miR-205-5p inhibitor compared to the mock-transfected controls at 24, 48, and 72 h. (c, d) The relative cell migration rates of KKU-213B cells transfected with miR-205-5p inhibitor at 12, 18, and 24 h and (e, f) invasion rates at 48 h compared to mock-transfected controls. The experiments were performed in triplicate and expressed as mean ± SD (*p < 0.05, **p < 0.01, ***p < 0.001).

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