Figure 1

Clinical course of CAIA and CTRL animals. Longitudinal development of (a) body weight, (b) grip strength, (c) semi-quantitative clinical arthritis score, and (d) ankle size for CAIA and CTRL animals (WT, αCGRP^-/-, Calcr^-/-) from day 315 following arthritis induction. Displayed are mean values and standard error of the mean (SEM).