Figure 8 | Scientific Reports

Figure 8

From: A CIC-related-epigenetic factors-based model associated with prediction, the tumor microenvironment and drug sensitivity in osteosarcoma

Figure 8

The role of risk score in drug sensitivity and immune therapy. (A) The correlation between risk score and drug sensitivity. Red represented a positive correlation, and green represented a negative correlation. (B) Scatter charts presented 3 drugs (XAV939, Entospletinib, and ERK_6604) most positively correlated with a risk score and 3 drugs (BI-2536, lapatinib, and Uprosertib) most negatively correlated with risk score. (C) The correlation of Tumor Inflammation Signature (TIS) with risk score. (D) The correlation of risk score with MHC molecules IPS (MHC_IPS), immunomodulators IPS (CP_IPS), effector cells IPS (EC_IPS), and suppressor cells IPS (SC_IPS). *P < 0.05, **P < 0.01, ***P < 0.001.

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