Table 1 Main characteristics of autism spectrum disorder patients with or without a history of maternal immune activation.

Numbers of patients

27

204

Offspring

 Male/female, n (%)

22/5 (81/19)

159/44 (78/22)

0.89

 Age at inclusion—month [mean (SD)]

78.22 (24.84)

89.55 (25.89)

0.03*

Pregnancy complications, n (%)

 Consanguinity

0 (0)

16 (7.8)

0.22

 Medically-assisted procreation

0 (0)

12 (5.88)

0.36

 History of spontaneous miscarriage

10 (37.03)

43 (21.07)

0.1

 Folate supplementation

16 (59.25)

86 (42.15)

0.14

 Threat of premature delivery

1 (3.70)

8 (3.92)

1

 Arterial hypertension

1 (3.70)

9 (4.41)

1

 Placenta previa

2 (7.40)

1 (0.49)

0.03*

 Premature rupture of membranes

2 (7.40)

2 (0.98)

0.06

 Intrauterine growth retardation

1 (3.70)

7 (3.43)

1

 Macrosomia

0 (0)

2 (0.98)

1

 Maternal-foetal infection

3 (11.1)

3 (1.47)

0.02*

Birth parameters, mean (SD)

 Birth term

38.53 (1.39)

38.58 (2.23)

0.06

 Birth height

48.84 (2.34)

49.46 (3.54)

0.04*

 Birth weight

3273 (452.01)

3289 (658.24)

0.47

 Head circumference

35.62 (3.78)

34.76 (3.02)

0.31

 1-min Apgar

9.44 (1.08)

9.44 (1.49)

0.43

 5-min Apgar

9.88 (0.42)

9.87 (0.73)

0.51

Biological parameters (univariate analysis)

 Neutrophils

3.30 (1.89)

3.15 (1.35)

0.90

 Lymphocytes

3.18 (1.70)

3.02 (1.12)

0.94

 Neutrophils/lymphocytes

1.42 (1.63)

1.17 (0.73)

0,81