Table 3 Lab trials examining the mortality induced by 5-HTR.426 yeast-ATSB in various mosquitoes.

From: Characterization of a novel RNAi yeast insecticide that silences mosquito 5-HT1 receptor genes

Species

Mortality ± SEM (%)

ASB

Control

5-HTR.426

P-value

n

A. aegypti

1 ± 1

2 ± 1

88 ± 1

 < 0.00001

180

A. albopictus

0 ± 0

0 ± 0

85 ± 2

 < 0.00001

225

A. gambiae

1 ± 1

1 ± 1

94 ± 1

 < 0.00001

180

C. quinquefasciatus

1 ± 1

1 ± 1

91 ± 1

 < 0.00001

225

C. pipiens

2 ± 1

2 ± 1

82 ± 3

 < 0.00001

225

  1. The average percent morbidity rates for A. aegypti, A. albopictus, A. gambiae, C. quinquefasciatus and C. pipiens adult females that were fed with lab attractive sugar bait (ASB) alone and yeast expressing the 5-HTR.426 or control shRNA are shown. The trials were performed in the insectary. The standard errors of the mean (SEMs) along with the total numbers of individuals subjected to each treatment (n) are provided. The p values obtained from one-way ANOVA conducted between individuals fed with attractive sugar bait alone (ASB) and 5-HTR.426- or control-yeast treated insects are provided.
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