Table 4 Delivery of RNAi yeast ATSB in a miniature sachet commercial bait system simulated field trial.

From: Characterization of a novel RNAi yeast insecticide that silences mosquito 5-HT1 receptor genes

Species

Mortality ± SEM (%)

ASB

Control

5-HTR.426

P-value

n

A. aegypti

8 ± 1

6 ± 1

97 ± 2

 < 0.00001

225

A. albopictus

6 ± 1

6 ± 2

96 ± 1

 < 0.00001

225

A. gambiae

6 ± 2

12 ± 4

98 ± 1

 < 0.00001

180

C. quinquefasciatus

4 ± 2

4 ± 2

100 ± 0

 < 0.00001

225

C. pipiens

2 ± 1

3 ± 1

99 ± 1

 < 0.00001

225

  1. The average percent morbidity rates for A. aegypti, A. albopictus, A. gambiae, C. quinquefasciatus and C. pipiens adult females that were fed with commercial attractive sugar bait (ASB) alone, bait containing yeast expressing 5-HTR.426 (5-HTR.426) or bait containing control yeast (control) within the miniature sachet membrane feeding systems are shown. The standard errors of the mean (SEMs) along with the total numbers of individuals subjected to each treatment (n) are also provided. The p values obtained from one-way ANOVA between individuals fed with ASB alone, 5-HTR.426 or control-treated adult mosquitoes are provided.
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