Figure 6
Phage cocktails (U1 + CR + M and U1 + M) along with colistin caused significant reduction in bioburden in infected zebrafish. Fish were infected with E. coli U1007 and 1 h post infection fish were grouped into untreated control and fish treated with bi-phage combination (U1 + M, U + C, M + C) and Tri-phage combination (U1 + M + CR) with and without colistin. 48 h after treatment, fish were euthanized, muscle tissues were dissected, macerated, serial diluted and plated onto LA plates. Plate counts were determined 24-48 h post incubation.. The experiment was performed in triplicates and the error bar represents their standard error of the mean. Student t test was performed to determine statistical significance of the variation among the treatment groups.
