Table 1 Characteristics of strains used for transformation and induction of resistance experiments.
Isolate | Species | Zoliflodacin MIC (mg/L)* | Azithromycin MIC (mg/L) | Ceftriaxone MIC (mg/L) | Ciprofloxacin MIC (mg/L) | Source of isolate |
|---|---|---|---|---|---|---|
9/1 | N. subflava | 0.5 | 3 | 0.023 | ND | Resistogenicity study15 |
45/1 | N. subflava | 2 | 6 | 0.047 | ND | Resistogenicity study |
773/3 | N. mucosa | 0.125 | 2 | 0.032 | 0.006 | PREGO/ComCom study16 |
801/1 | N. mucosa | 1 | ND | ND | ND | PREGO/ComCom study16 |
DSM4631 | N. mucosa | 0.5 | ND | ND | ND | Reference strain |
793/3 | N. macacae | 0.5 | ND | ND | ND | PREGO/ComCom study16 |
782/1 | N. cinerea | 0.125 | 2 | < 0.016 | 0.012 | PREGO/ComCom study16 |
761/1 | N. lactamica | 0.125 | 2 | < 0.016 | 0.19 | PREGO/ComCom study16 |
ATCC49226 | N. gonorrhoeae | 0.125 | 0.25 | < 0.016 | 0.003 | Reference strain |
WHO F | N. gonorrhoeae | 0.032 | 0.125 | < 0.016 | 0.004 | WHO reference strain34 |
WHO P | N. gonorrhoeae | 0.125 | 4 | 0.004 | 0.004 | WHO reference strain34 |
WHO X | N. gonorrhoeae | 0.125 | 0.25 | 1.5 | > 32 | WHO reference strain34 |
WHO Z | N. gonorrhoeae | 0.125 | 0.75 | 0.5 | > 32 | WHO reference strain34 |
38/1 | N. gonorrhoeae | 0.125 | 0.25 | 0.016 | ND | Resistogenicity study15 |
