Figure 4
Construction and evaluation of a DSP prognostic signature for CRC. (a) Univariate Cox analysis about DSP-related genes differential expression in colorectal cancer and normal tissue. (b, c) LASSO regression analysis of DSP-related genes which are most significantly correlated with OS. Survival analysis of CRC patients in the (d) training and (e) testing datasets. Signature gene expression in the high- and low-risk groups in the (f) training and (g) testing datasets. Risk scores of patients in the high- and low-risk groups in the (h) training and (i) testing cohorts. Survival status of each patient in the (j) training and (k) testing datasets. DSP, disulfidptosis. LASSO, least absolute shrinkage and selection operator; OS, overall survival; CRC, colorectal cancer. *P < 0.05, **P < 0.01, and ***P < 0.001.
