Table 4 Metabolites identified by high-resolution mass spectrometry with significant changes caused by fructose exposure in liver.
Component name | Formula | Retention time | Adduct/charge | Precursor mass | Fold regulation | P value | Corrected P value# |
|---|---|---|---|---|---|---|---|
Calcidiol | C27H44O2 | 15.27 | [M + H]+ | 401.341 | 4.45 | 0.27*10–2 | 0.04 |
19,20-DiHDPA | C22H34O4 | 9.67 | [M + H]+ | 363.253 | 4.26 | 0.51*10–2 | 0.05 |
PGF2a ethanolamide | C22H39NO5 | 9.69 | [M + H]+ | 398.29 | 3.56 | 0.73*10–2 | 0.05 |
Hydroxyindole-acetaldehyde | C10H9NO2 | 1.77 | [M + H]+ | 176.071 | 0.47 | 0.82*10–2 | 0.05 |
Indoleacetic acid | C10H9NO2 | 1.77 | [M + H]+ | 176.071 | 0.47 | 0.81*10–2 | 0.05 |
Stearoyl-ethanolamide | C20H41NO2 | 14.38 | [M + H]+ | 328.321 | 2.83 | 0.87*10–2 | 0.05 |
Guanidino-succinic acid | C5H9N3O4 | 1.76 | [M + H]+ | 176.067 | 0.48 | 0.01 | 0.05 |
Glyceraldehyde | C3H6O3 | 2.22 | [M-H]- | 89.024 | 0.48 | 0.01 | 0.04 |
Palmitoyl-ethanolamide | C18H37NO2 | 13.57 | [M + H]+ | 300.29 | 2.02 | 0.01 | 0.04 |
Taurodeoxycholic acid 3-glucuronide | C32H53NO12S | 9.37 | [M-H]- | 674.322 | 0.02 | 0.02 | 0.05 |
