Table 1 Summary of association between Trop 2 staining and clinical-pathologic variables at radical prostatectomy.
Variable | Trop 2 Negative (N = 389) | Trop 2 Positive (N = 764) | p-value |
|---|---|---|---|
Gleason score | |||
 ≤ 6 | 222 (56%) | 326 (43%) |  |
 7 | 122 (32%) | 327 (43%) |  |
 ≥ 8 | 45 (12%) | 111 (14%) |  < 0.001& |
P-stage | |||
 T2 | 256 (70%) | 491 (66%) |  |
 T3/T4 | 110 (30%) | 258 (34%) | 0.163& |
Age (years) | |||
 Median | 62 | 63 | 0.023+ |
Pre-op PSA (ng/mL) | |||
 Median | 6.48 | 6.81 | 0.017+ |
Surgical margins | |||
 Negative | 259 (71%) | 471 (65%) | 0.052& |
 Positive | 107 (29%) | 257 (35%) |  |
ECE | |||
 No | 267 (79%) | 511 (68%) | 0.489& |
 Yes | 114 (30%) | 242 (32%) |  |
Seminal vesicle invasion | |||
 No | 358 (93%) | 706 (94%) | 0.710& |
 Yes | 27 (7%) | 47 (6%) |  |