Table 1 Summary of association between Trop 2 staining and clinical-pathologic variables at radical prostatectomy.

From: High expression of Trop2 is associated with aggressive localized prostate cancer and is a candidate urinary biomarker

Variable

Trop 2 Negative (N = 389)

Trop 2 Positive (N = 764)

p-value

Gleason score

 ≤ 6

222 (56%)

326 (43%)

 

 7

122 (32%)

327 (43%)

 

 ≥ 8

45 (12%)

111 (14%)

 < 0.001&

P-stage

 T2

256 (70%)

491 (66%)

 

 T3/T4

110 (30%)

258 (34%)

0.163&

Age (years)

 Median

62

63

0.023+

Pre-op PSA (ng/mL)

 Median

6.48

6.81

0.017+

Surgical margins

 Negative

259 (71%)

471 (65%)

0.052&

 Positive

107 (29%)

257 (35%)

 

ECE

 No

267 (79%)

511 (68%)

0.489&

 Yes

114 (30%)

242 (32%)

 

Seminal vesicle invasion

 No

358 (93%)

706 (94%)

0.710&

 Yes

27 (7%)

47 (6%)

 
  1. +Wilcoxon Test; &Pearson Chi-Squared Test.