Table 2 List of the differentially expressed miRNAs identified with the EdgeR and DESeq2 algorithms in the peripheral blood samples of animals with diffuse lesions vs controls and animals with diffuse vs focal lesions.

From: MicroRNAs modulate immunological and inflammatory responses in Holstein cattle naturally infected with Mycobacterium avium subsp. paratuberculosis

Comparison

Algorithm

miRNA name

Fold change (log2)

Adjusted p-value

Diffuse lesions vs controls

DESeq2

bta-miR-2425-3p

5.760949308

0.000901

bta-miR-144

−3.614670202

0.002987

bta-miR-19a

−2.643658463

0.011826

bta-miR-32

−2.628257174

0.049391

bta-miR-139

1.841533295

0.049391

bta-miR-101

−2.375232972

0.049391

EdgeR

bta-miR-144

−3.523181922

0.000791

bta-miR-27a-5p

−3.686888682

0.003369

bta-miR-2425-3p

5.698593367

0.005617

bta-miR-19a

−2.5239869

0.011452

bta-miR-101

−2.218090784

0.036952

bta-miR-139

1.914828963

0.036952

bta-miR-181a

−1.860477015

0.036952

Diffuse vs focal lesions

DESeq2

bta-miR-19a

−3.071981051

2.96E−05

bta-miR-144

−3.798502613

2.96E−05

bta-miR-32

−2.958950883

0.001641

EdgeR

bta-miR-144

−3.91750149

0.001931

bta-miR-19a

−3.182992869

0.001931

bta-miR-32

−3.05395378

0.003893