Table 2 Feature importances for the classifier predicting three levels of MGD from relative protein quantifications using SHAP weighted by model uncertainty.
Rank | Protein (accession number), incl. BL | Protein (accession number), excl. BL |
|---|---|---|
1 | Ubiquitin-conjugating enzyme E2 variant 1 (Q13404) | Polymeric immunoglobulin receptor (P01833) |
2 | Endoplasmic reticulum resident protein 29 (P30040) | Mannose-1-phosphate guanyltransferase alpha (Q96IJ6) |
3 | Polymeric immunoglobulin receptor (P01833) | Tissue alpha-L-fucosidase (P04066) |
4 | Tissue alpha-L-fucosidase (P04066) | Ubiquitin-conjugating enzyme E2 variant 1 (Q13404) |
5 | Malate dehydrogenase, cytoplasmic (P40925) | Heterogeneous nuclear ribonucleoprotein M (P52272) |
6 | Prostaglandin reductase 1 (Q14914) | Endoplasmic reticulum resident protein 29 (P30040) |
7 | Mannose-1-phosphate guanyltransferase alpha (Q96IJ6) | IGKV2-24 (A0A0C4DH68) |
8 | IGKV2-24 (A0A0C4DH68) | 40S ribosomal protein SA (P08865) |
9 | Glutathione peroxidase 1 (P07203) | Prostaglandin reductase 1 (Q14914) |
10 | IGG1 (P0DOX5) | UDP-glucose 4-epimerase (Q14376) |
11 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (Q8TBX8) | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (Q8TBX8) |
12 | Heterogeneous nuclear ribonucleoprotein M (P52272) | PRP4 (Q16378) |
13 | Psoriasin (P31151) | Protein S100-A8 (P05109) |
14 | ADH7 (P40394) | SH2 domain-containing protein 4A (Q9H788) |
15 | PRP4 (Q16378) | Malate dehydrogenase, cytoplasmic (P40925) |
