Table 5 Multivariate analysis of clinical characteristics on RFS and OS.

Age

0.999 (0.972–1.027)

0.957 (0.957)

1.012 (0.971–1.055)

1.040 (0.578)

0.952 (0.888–1.021)

0.272 (0.170)

Sex (Female vs. Male)

1.148 (0.554–2.379)

0.800 (0.711)

1.237 (0.476–3.210)

0.852 (0.663)

1.958 (0.373–10.29)

0.488 (0.427)

Smoking status (No vs. Yes)

0.749 (0.355–1.581)

0.806 (0.448)

0.535 (0.217–1.320)

0.394 (0.175

NA

–

Pathological stage

2.645 (1.786–3.919

 < 0.001 (< 0.001)

3.377 (1.897–6.012)

< 0.001 (< 0.001)

3.694 (1.512–9.023)

0.032 (0.004)

Adjuvant therapy (No vs. Yes)

0.749 (0.380–1.477)

0.909 (0.404)

0.780 (0.271–2.250)

0.769 (0.646)

0.152 (0.021–1.091)

0.122 (0.061)

CRP

1.043 (0.901–1.206)

0.735 (0.572)

1.057 (0.810–1.380)

0.769 (0.684)

0.878 (0.584- 1.318)

0.529 (0.529)

NLR

1.024 (0.951–1.101)

0.799 (0.533)

0.989 (0.813–1.204)

0.916 (0.916)

2.262 (1.230–4.160)

0.036 (0.009)

LMR

1.133 (0.914–1.406)

0.762 (0.254)

1.274 (0.924–1.755)

0.417 (0.139)

1.300 (0.762–2.217)

0.447 (0.335)

PLR

1.004 (1.001–1.00)

0.085 (0.019)

1.006 (1.000–1.011)

0.222 (0.049)

0.989 (0.979–0.999)

0.067 (0.025)

Age

0.920 (0.833–1.016)

0.150 (0.100)

Sex (Female vs. Male)

NA

–

Smoking status (No vs. Yes)

NA

–

Pathological stage

4.925 (1.304–18.60)

0.114 (0.019)

Adjuvant therapy (No vs. Yes)

NA

–

CRP

1.311 (0.980–1.755)

0.204 (0.068)

NLR

1.423 (0.403–5.027)

0.701 (0.584)

LMR

1.944 (0.920–4.108)

0.162 (0.081)

PLR

0.996 (0.980–1.012)

0.624 (0.624)