Table 3 Overview of the top significant CNVRs associated with all studied traits in American mink.

From: Genome-wide association studies for economically important traits in mink using copy number variation

CNVR ID

Type

Chromosome

Start position

End position

Length (bp)

Associated traits

P-value

Candidate genes

CNVR54

Duplication

2

76,047,394

76,080,498

33,104

TB

3.58E−14

–

CNVR112

Deletion

5

45,720,950

45,756,856

35,906

DPS

1.26E−13

ITGA3, LOC122907723

CNVR203

Duplication

11

119,613,197

119,626,953

13,756

AWW

1.44E−13

LOC122890709, LOC122889431

CNVR126

Duplication

6

143,324,461

143,377,043

52,582

HW

3.48E−13

–

CNVR1

Duplication

1

10,430,780

10,527,641

96,861

FCR

5.35E−13

ARID1B

CNVR113

Deletion

5

158,304,905

158,351,587

46,682

DQU

6.26E−13

METTL21C, BIVM, CCDC168

CNVR200

Duplication

11

208,363,505

208,379,126

15,621

AWB

2.24E−12

DLGAP2

CNVR56

Duplication

2

51,828,542

51,834,524

5982

LW

2.95E−12

–

CNVR20

Duplication

1

48,882,466

48,894,690

12,224

GL

3.08E−12

BCKDHB

CNVR54

Duplication

2

76,047,394

76,080,498

33,104

LQU

8.35E−12

–

CNVR216

Deletion

11

71,374,870

71,389,512

14,642

SW

5.42E−10

TBC1D9

CNVR90

Duplication

4

201,592,245

201,635,594

43,349

SB

1.71E−09

KCND2

CNVR238

Duplication

13

139,238,384

139,379,378

140,994

RFI

7.32E−09

–

CNVR235

Duplication

13

26,765,710

26,829,160

63,450

CIEP

1.98E−07

–

CNVR40

Duplication

2

237,951,459

238,012,681

61,222

ELISA_G

5.81E−07

–

CNVR159

Deletion

7

130,788,259

130,823,564

35,305

LNAP

1.9E−06

PIWIL4

CNVR2

Duplication

1

133,977,608

134,011,851

34,243

KR

2.64E−06

SYCP2L

CNVR13

Duplication

1

75,139,496

75,250,132

110,636

RIG

3.97E−06

–

CNVR1

Duplication

1

10,430,780

10,527,641

96,861

ADG

6.29E−06

ARID1B

CNVR179

Duplication

9

12,654,424

12,657,997

3573

DNAP

6.66E−06

TTLL11

CNVR70

Duplication

3

46,223,063

46,323,843

100,780

LB

7.80E−06

NDUFA10

CNVR9

Duplication

1

282,031,840

282,086,441

54,601

HL

9.33E−06

–

CNVR192

Duplication

11

56,914,479

56,922,804

8325

ELISA_P

4.19E−05

LOC122890225

CNVR4

Duplication

1

119,299,899

119,337,598

37,699

DFI

1.53E−04

HSD17B8, SLC39A7, RXRB, COL11A2

CNVR75

Duplication

4

75,332,844

75,473,471

140,627

FBW

1.81E−04

TOX

CNVR12

Duplication

1

11,780,319

11,833,194

52,875

RG

2.84E−04

NOX3

CNVR125

Duplication

6

198,790,330

198,804,380

14,050

FBL

4.27E−04

ASB14, DNAH12, APPL1

  1. TB: total number of kits born, DPS: dried pelt size, AWW: average kit weight per litter at weaning, HW: harvest weight, FCR: feed conversion ratio, DQU: overall quality of dried pelt, AWB: average kit weight per litter at birth, LW: number of kits alive at weaning, GL: gestation length, LQU: live grading overall quality of fur, SW: survival rate at weaning, SB: survival rate at birth, RFI: residual feed intake, CIEP: counterimmunoelectrophoresis test, ELISA_G: AMDV-G based enzyme-linked immunosorbent assay test, LNAP: Live grading nap size, KR: Kleiber ratio, RIG: residual intake and gain, ADG: average daily gain, DNAP: dried pelt nap size, LB: number of kits alive at birth, HL: harvest length, ELISA_P: VP2 based enzyme-linked immunosorbent assay test, DFI: daily feed intake, FBW: final body weight, RG: residual gain, FBL: final body length.