Table 4 Odds ratio of %C3-epi-25(OH)D3 to 10 specific diseases in different seasons.

From: C3-epi-25(OH)D3 percentage, not level, may be a potential biomarker to reflect its pathological increase in multiple diseases: a cross-sectional case–control study

Diseases

Spring

Summer

Autumn

Winter

n

OR(95%CI)

Waldχ2

P

n

OR(95%CI)

Waldχ2

P

n

OR(95%CI)

Waldχ2

P

n

OR(95%CI)

Waldχ2

P

Abortion

42

1.25(1.10, 1.43)

10.971

0.001

53

1.20(1.08, 1.33)

11.841

0.001

23

1.18(1.00, 1.39)

3.854

0.049

14

1.11(0.93, 1.33)

1.266

0.261

Acyesis

79

1.24(1.06, 1.45)

6.918

0.009

79

1.36(1.22, 1.51)

31.939

 < 0.001

49

1.35(1.09, 1.67)

7.544

0.006

47

1.15(0.90, 1.47)

1.202

0.273

Osteoporosis

117

1.15(1.05, 1.25)

9.005

0.003

114

1.26(1.16, 1.37)

32.002

 < 0.001

113

1.36(1.23, 1.49)

38.494

 < 0.001

93

1.15(1.01, 1.30)

4.635

0.031

Arthritis

292

1.09(1.01, 1.17)

5.062

0.024

363

1.25(1.18, 1.32)

61.504

 < 0.001

195

1.28(1.18, 1.38)

37.079

 < 0.001

158

1.18(1.06, 1.31)

8.802

0.003

Disk herniation

75

1.15(1.04, 1.27)

7.524

0.006

83

1.14(1.03, 1.26)

5.930

0.015

39

1.15(0.97, 1.36)

2.651

0.103

44

1.22(1.06, 1.41)

7.590

0.006

Muscle pain

38

1.17(1.03, 1.33)

5.952

0.015

64

1.12(1.00, 1.26)

3.911

0.048

32

1.37(1.17, 1.61)

15.383

 < 0.001

29

1.09(0.89, 1.32)

0.695

0.404

Metabolic syndrome

47

1.15(1.01, 1.32)

4.116

0.040

18

1.42(1.24, 1.63)

24.464

 < 0.001

25

1.16(0.93, 1.44)

1.731

0.188

19

1.24(1.01, 1.51)

4.474

0.023

Menopausal syndrome

39

1.15(1.00, 1.32)

4.083

0.043

35

1.17(1.00, 1.37)

4.028

0.045

25

1.15(0.92, 1.43)

1.535

0.215

23

1.33(1.12, 1.58)

10.142

0.001

Diabetes mellitus

220

1.18(1.10, 1.27)

19.173

 < 0.001

94

1.05(0.94, 1.16)

0.770

0.380

20

1.25(1.01, 1.55)

4.031

0.045

45

1.32(1.16, 1.51)

17.676

 < 0.001

Sjogren syndrome

28

1.13(0.96, 1.33)

2.137

0.144

43

1.16(1.01, 1.33)

4.351

0.037

28

1.30(1.08, 1.56)

7.535

0.006

29

1.19(1.00, 1.41)

3.976

0.046

  1. The multinomial logistic regression was used. All the OR values has been adjusted by gender, age, and season. In the 10 specific diseases, %C3-epi-25(OH)D3 can predict the disease risk throughout or nearly throughout the whole four seasons. Its predictive ability can vary from season to season. Significant values are in bold.
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