Table 4 Relationship between HDL-C levels and reversion to normoglycemia from Pre-DM in different models.

From: Association between high-density lipoprotein cholesterol and reversion to normoglycemia from prediabetes: an analysis based on data from a retrospective cohort study

Exposure

Model 1 (HR., 95% CI, P)

Model 2 (HR, 95% CI, P)

Model 3 (HR, 95% CI, P)

Model 4 (HR, 95% CI, P)

HDL-C

1.920 (1.798, 2.050) < 0.001

1.883 (1.752, 2.023) < 0.001

1.898 (1.758, 2.048) < 0.001

1.948 (1.804, 2.102) < 0.001

HDL-C (quartiles)

 Q1

ref

ref

ref

ref

 Q2

1.244 (1.159, 1.335) < 0.001

1.212 (1.129, 1.301) < 0.001

1.198 (1.115, 1.288) < 0.001

1.204 (1.120, 1.294) < 0.001

 Q3

1.569 (1.463, 1.682) < 0.001

1.487 (1.385, 1.597) < 0.001

1.470 (1.368, 1.580) < 0.001

1.491 (1.385, 1.604) < 0.001

 Q4

1.794 (1.675, 1.922) < 0.001

1.742 (1.620, 1.873) < 0.001

1.733 (1.609, 1.866) < 0.001

1.767 (1.637, 1.908) < 0.001

P for trend

 < 0.001

 < 0.001

 < 0.001

 < 0.001

  1. Model 1: we did not adjust for other covariants.
  2. Model 2: we adjusted for DBP, SBP, BMI, gender, age, drinking status, family history of diabetes, and smoking status.
  3. Model 3: we adjusted for DBP, SBP, BMI, gender, age, drinking status, family history of diabetes, smoking status, FPG, AST, BUN, ALT, LDL-C, Scr, and TG.
  4. Model 4: we adjusted for DBP (smooth), age (smooth), sex, SBP (smooth), BMI (smooth), drinking status, family history of diabetes, smoking status, FPG (smooth), AST (smooth), BUN(smooth), ALT(smooth), LDL-C (smooth), Scr (smooth), and TG (smooth).
  5. HR hazard ratios, CI confidence interval, Ref reference, GAM generalized additive mode, HDL-C high-density lipoprotein cholesterol.
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