Table 1 Optimal cut-points (maximum sensitivity + specificity) for K (age-corrected) at each lobe (Frontal, F; Occipital, O; Parietal, P, and Temporal, T). Cut-points, accuracy, sensibility, and specificity for discriminating pairwise diagnostic groups.

From: Cortical folding correlates to aging and Alzheimer’s Disease’s cognitive and CSF biomarkers

Lobes

CTL-AD

CTL-MCI

Cut-point

AUC

ACC

SENS

SPEC

Cut-point

AUC

ACC

SENS

SPEC

F

− 0.46

0.70

0.73

0.46

0.78

− 0.45

0.55

0.5

0.54

0.48

O

− 0.35

0.67

0.73

0.5

0.77

− 0.33

0.56

0.45

0.79

0.32

P

− 0.34

0.79

0.72

0.77

0.72

− 0.34

0.47

0.64

0.30

0.77

T

− 0.34

0.75

0.67

0.61

0.68

− 0.34

0.59

0.69

0.41

0.80

  1. AUC area under the curve, ACC accuracy, SENS sensibility, and SPEC Specificity. ROI codes: F, frontal; O, occipital; P, parietal, and T, temporal lobes.
Back to article page